Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9426845 | 0.90 | CYP2D6 (0.50) | HTR2ATHRBKMT2ASMN1; SMN2NLRP3 | |
| SCHEMBL9425985 | 0.89 | THRB (0.51) | HTR2ATHRBKMT2ASMN1; SMN2NLRP3 | |
| SCHEMBL9321227 | 0.88 | POLB (0.49) | HTR2ATHRBKMT2ASMN1; SMN2NLRP3 | |
| SCHEMBL9426465 | 0.88 | HPGD (0.52) | HTR2ATHRBKMT2ASMN1; SMN2NLRP3 | |
| Hydrochloric Acid SCHEMBL9426244 | 0.86 | AVPR2 (0.52) | HTR2ATHRBKMT2ASMN1; SMN2NLRP3 | |
| SCHEMBL9513197 | 0.85 | THRB (0.58) | HTR2ATHRBKMT2ASMN1; SMN2POLB | |
| SCHEMBL9320194 | 0.84 | THRB (0.65) | HTR2ATHRBKMT2APOLBHPGD | |
| Hydrochloric Acid SCHEMBL9512922 | 0.84 | THRB (0.57) | HTR2ATHRBKMT2ASMN1; SMN2POLB | |
| SCHEMBL9320513 | 0.83 | LMNA (0.59) | HTR2ATHRBKMT2ASMN1; SMN2NLRP3 | |
| Dimethylamine SCHEMBL9320437 | 0.83 | THRB (0.63) | HTR2ATHRBKMT2APOLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5321027-A | Analgesic | CIBA-GEIGY CORPORATION (US) | 1994-06-14 | — | — | US | disclosed |
| EP-0489690-A1 | Substituted N-Benzoyl-N'-(2-phenylethyl)-piperazines | CIBA-GEIGY AG (CH) | 1992-06-10 | — | — | EP | disclosed |