Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | AOC1 | P19801 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9426618 | 0.88 | HTT (0.51) | ALDH1A1KMT2AGAASMN1; SMN2LMNA | |
| SCHEMBL9426614 | 0.85 | LMNA (0.62) | ALDH1A1KMT2AGAASMN1; SMN2LMNA | |
| SCHEMBL9425432 | 0.82 | ALDH1A1 (0.45) | ALDH1A1KMT2AGAASMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL9426498 | 0.81 | ALDH1A1 (0.44) | ALDH1A1KMT2AGAASMN1; SMN2LMNA | |
| SCHEMBL9586194 | 0.79 | LMNA (0.43) | ALDH1A1GAASMN1; SMN2LMNAHTT | |
| SCHEMBL9425715 | 0.78 | SMN1; SMN2 (0.43) | ALDH1A1KMT2AGAASMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL9425881 | 0.77 | SMN1; SMN2 (0.42) | ALDH1A1KMT2AGAASMN1; SMN2LMNA | |
| SCHEMBL6988265 | 0.76 | CYP1A2 (0.41) | ALDH1A1KMT2AGAACA1CA9 | |
| SCHEMBL6988259 | 0.75 | GAA (0.39) | ALDH1A1KMT2AGAAAOC1AOC3 | |
| Hydrochloric Acid SCHEMBL9426022 | 0.75 | CYP1A2 (0.40) | ALDH1A1GAACA1CA9AOC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5371086-A | Circulatory disorders side effect reduction | THE GREEN CROSS CORPORATION (JP) | 1994-12-06 | — | — | US | disclosed |
| US-5262415-A | FOR TREATING DISEASES OF THE CIRCULATORY SYSTEM | THE GREEN CROSS CORPORATION (JP) | 1993-11-16 | — | — | US | disclosed |
| EP-0503627-A1 | Aminopyridine compounds | THE GREEN CROSS CORPORATION (JP) | 1992-09-16 | — | — | EP | disclosed |