Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | AOC1 | P19801 | 2/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | APAF1 | O14727 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9426526 | 0.80 | ALOX12 (0.46) | LMNAHTTPOLBAOC1AOC3 | |
| SCHEMBL9426257 | 0.79 | ALDH1A1 (0.49) | LMNAHTTAOC1AOC3ALDH1A1 | |
| SCHEMBL9425432 | 0.76 | ALDH1A1 (0.45) | LMNAAOC1AOC3ALDH1A1MAPT | |
| SCHEMBL9426618 | 0.76 | HTT (0.51) | LMNAHTTALDH1A1MAPTKDM4E | |
| Hydrochloric Acid SCHEMBL9426498 | 0.75 | ALDH1A1 (0.44) | LMNAAOC1AOC3ALDH1A1MAPT | |
| SCHEMBL9426614 | 0.74 | LMNA (0.62) | LMNAHTTALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9425715 | 0.73 | SMN1; SMN2 (0.43) | LMNAHTTPOLBALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL9425881 | 0.71 | SMN1; SMN2 (0.42) | LMNAHTTPOLBAOC1AOC3 | |
| SCHEMBL6988265 | 0.71 | CYP1A2 (0.41) | ALDH1A1MAPTKDM4ETHRBCA1 | |
| SCHEMBL18858121 | 0.70 | GAA (0.39) | AOC1AOC3ALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5262415-A | FOR TREATING DISEASES OF THE CIRCULATORY SYSTEM | THE GREEN CROSS CORPORATION (JP) | 1993-11-16 | — | — | US | disclosed |