Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GALR3 | O60755 | 1/20 | 0.41 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.41 |
| ▸ | KDM6B | O15054 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | QPCT | Q16769 | 1/20 | 0.38 |
| ▸ | BCL6 | P41182 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9426614 | 0.92 | LMNA (0.62) | HTTALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL9426257 | 0.88 | ALDH1A1 (0.49) | HTTALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL9425432 | 0.80 | ALDH1A1 (0.45) | ALDH1A1LMNASMN1; SMN2KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL9426498 | 0.78 | ALDH1A1 (0.44) | ALDH1A1LMNASMN1; SMN2KMT2AMAPT | |
| SCHEMBL9586194 | 0.76 | LMNA (0.43) | HTTALDH1A1LMNASMN1; SMN2MAPT | |
| SCHEMBL3068769 | 0.76 | KDM4C (0.57) | GAAKDM6BKDM4C | |
| SCHEMBL9425715 | 0.76 | SMN1; SMN2 (0.43) | HTTALDH1A1LMNASMN1; SMN2KMT2A | |
| Hydrochloric Acid SCHEMBL9425881 | 0.75 | SMN1; SMN2 (0.42) | HTTALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL6988265 | 0.74 | CYP1A2 (0.41) | ALDH1A1KMT2ACYP1A2MAPTGAA | |
| Hydrochloric Acid SCHEMBL9426022 | 0.73 | CYP1A2 (0.40) | ALDH1A1CYP1A2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5371086-A | Circulatory disorders side effect reduction | THE GREEN CROSS CORPORATION (JP) | 1994-12-06 | — | — | US | disclosed |
| US-5262415-A | FOR TREATING DISEASES OF THE CIRCULATORY SYSTEM | THE GREEN CROSS CORPORATION (JP) | 1993-11-16 | — | — | US | disclosed |
| EP-0503627-A1 | Aminopyridine compounds | THE GREEN CROSS CORPORATION (JP) | 1992-09-16 | — | — | EP | disclosed |