Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9425881 | 0.98 | SMN1; SMN2 (0.42) | SMN1; SMN2POLBHPGDHTTALDH1A1 | |
| SCHEMBL9425432 | 0.82 | ALDH1A1 (0.45) | SMN1; SMN2ALDH1A1KMT2AMEN1MAPT | |
| Hydrochloric Acid SCHEMBL9426498 | 0.81 | ALDH1A1 (0.44) | SMN1; SMN2ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL9426526 | 0.80 | ALOX12 (0.46) | SMN1; SMN2POLBHTTALDH1A1KMT2A | |
| SCHEMBL9426257 | 0.78 | ALDH1A1 (0.49) | SMN1; SMN2HPGDHTTALDH1A1KMT2A | |
| SCHEMBL6988265 | 0.76 | CYP1A2 (0.41) | ALDH1A1KMT2AMEN1MAPTCYP1A2 | |
| SCHEMBL9426618 | 0.76 | HTT (0.51) | SMN1; SMN2HTTALDH1A1KMT2AMAPT | |
| SCHEMBL18858121 | 0.75 | GAA (0.39) | ALDH1A1KMT2AMEN1MAPTGAA | |
| SCHEMBL15432255 | 0.75 | GAA (0.39) | HTTALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL6988259 | 0.75 | GAA (0.39) | ALDH1A1KMT2AMEN1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5371086-A | Circulatory disorders side effect reduction | THE GREEN CROSS CORPORATION (JP) | 1994-12-06 | — | — | US | disclosed |
| US-5262415-A | FOR TREATING DISEASES OF THE CIRCULATORY SYSTEM | THE GREEN CROSS CORPORATION (JP) | 1993-11-16 | — | — | US | disclosed |
| EP-0503627-A1 | Aminopyridine compounds | THE GREEN CROSS CORPORATION (JP) | 1992-09-16 | — | — | EP | disclosed |