Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 7/20 | 0.44 |
| ▸ | HTR1A | P08908 | 5/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.44 |
| ▸ | DRD2 | P14416 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
| ▸ | HTR2B | P41595 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9428336 | 0.94 | HRH1 (0.48) | MEN1ALDH1A1KMT2AHRH1HTR1A | |
| SCHEMBL9429100 | 0.93 | HRH1 (0.49) | MEN1ALDH1A1KMT2AHRH1HTR1A | |
| Oxalic Acid SCHEMBL9430076 | 0.89 | ALDH1A1 (0.49) | MEN1ALDH1A1KMT2AHRH1HTR1A | |
| SCHEMBL9429366 | 0.84 | ALDH1A1 (0.52) | LTA4HMEN1ALDH1A1KMT2AHRH1 | |
| SCHEMBL9429465 | 0.83 | MAPT (0.52) | MEN1ALDH1A1KMT2AHRH1HTR1A | |
| Hydrochloric Acid SCHEMBL9428580 | 0.83 | MEN1 (0.51) | LTA4HMEN1ALDH1A1KMT2AHRH1 | |
| SCHEMBL9428616 | 0.82 | DRD2 (0.44) | MEN1ALDH1A1KMT2AHRH1HTR1A | |
| SCHEMBL9429697 | 0.81 | DRD2 (0.57) | ALDH1A1HRH1HTR1AADRA1ADRD2 | |
| SCHEMBL9429282 | 0.81 | KDM4E (0.54) | MEN1ALDH1A1KMT2AHRH1HTR1A | |
| SCHEMBL9429005 | 0.81 | CYP2C19 (0.53) | MEN1ALDH1A1KMT2AHRH1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332739-A | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-07-26 | — | — | US | disclosed |
| EP-0454498-A2 | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-10-30 | — | — | EP | disclosed |