Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | RORC | P51449 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPY1R | P25929 | 1/20 | 0.44 |
| ▸ | NPY2R | P49146 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9429944 | 0.89 | KDM4E (0.53) | KDM4EMAPTMEN1KMT2AHIF1A | |
| SCHEMBL9429412 | 0.88 | HIF1A (0.56) | KDM4EMAPTPTGS1HIF1ACYP1A2 | |
| SCHEMBL9428554 | 0.85 | PTGS1 (0.50) | MAPTPTGS1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9429463 | 0.84 | PTGS2 (0.52) | PTGS1PTGS2RORCSMN1; SMN2 | |
| SCHEMBL9429668 | 0.80 | HIF1A (0.57) | KDM4EMAPTPTGS1HIF1ACYP1A2 | |
| SCHEMBL2565690 | 0.79 | PTGS1 (0.65) | KDM4EMAPTPTGS1MEN1KMT2A | |
| SCHEMBL9429341 | 0.76 | MAPT (0.58) | MAPTRORCSMN1; SMN2NPC1RAB9A | |
| SCHEMBL9429300 | 0.75 | SMN1; SMN2 (0.52) | PTGS2RORCSMN1; SMN2 | |
| SCHEMBL9428655 | 0.75 | PTGS2 (0.51) | MAPTMEN1KMT2APTGS2SMN1; SMN2 | |
| SCHEMBL12000495 | 0.73 | PTGS1 (0.60) | KDM4EMAPTPTGS1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5328907-A | Treatment of allograft rejection in mammals and antiinflammatory agents | SYNTEX (U.S.A.) INC. (US) | 1994-07-12 | — | — | US | disclosed |
| US-5108999-A | For treating inflammation, autoimmune disease or allograft rejection in mammals | SYNTEX (U.S.A.) INC. (US) | 1992-04-28 | — | — | US | disclosed |