Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 3/20 | 0.45 |
| ▸ | HTR2C | P28335 | 2/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.44 |
| ▸ | EBP | Q15125 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9385849 | 0.81 | HTR1A (0.51) | ALDH1A1MEN1KMT2AHTR1AHRH1 | |
| SCHEMBL9428322 | 0.79 | SLC6A3 (0.57) | ALDH1A1MEN1KMT2AHTR1ASIGMAR1 | |
| SCHEMBL9428318 | 0.78 | MEN1 (0.54) | ALDH1A1MEN1KMT2AADRA1BADRA1A | |
| SCHEMBL9428246 | 0.77 | MEN1 (0.52) | ALDH1A1MEN1KMT2AHTR1AADRA1B | |
| SCHEMBL9428716 | 0.77 | ALDH1A1 (0.52) | ALDH1A1MEN1KMT2AHTR1AADRA1B | |
| SCHEMBL9429643 | 0.77 | MEN1 (0.55) | ALDH1A1MEN1KMT2AHTR1AADRA1B | |
| Hydrochloric Acid SCHEMBL9428320 | 0.76 | MEN1 (0.51) | ALDH1A1MEN1KMT2AHTR1AADRA1B | |
| Hydrochloric Acid SCHEMBL9428451 | 0.76 | MEN1 (0.54) | ALDH1A1MEN1KMT2AHTR1AADRA1B | |
| SCHEMBL9428993 | 0.75 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2AADRA1BADRA1A | |
| SCHEMBL5183284 | 0.74 | SIGMAR1 (0.47) | ADRA1BADRA1AADRA1DEBPSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332739-A | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-07-26 | — | — | US | disclosed |
| EP-0454498-A2 | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-10-30 | — | — | EP | disclosed |