Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 2/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.45 |
| ▸ | HRH1 | P35367 | 3/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9429643 | 0.86 | MEN1 (0.55) | SLC6A3MEN1ALDH1A1KMT2ADRD2 | |
| Hydrochloric Acid SCHEMBL9428451 | 0.85 | MEN1 (0.54) | MEN1ALDH1A1KMT2ADRD2SIGMAR1 | |
| SCHEMBL9385183 | 0.81 | SIGMAR1 (0.60) | MEN1ALDH1A1KMT2ADRD2HTR2A | |
| SCHEMBL9428590 | 0.80 | DRD2 (0.48) | MEN1ALDH1A1KMT2ADRD2SLC6A4 | |
| SCHEMBL9428318 | 0.80 | MEN1 (0.54) | MEN1ALDH1A1KMT2AHRH1 | |
| SCHEMBL9428804 | 0.79 | ALDH1A1 (0.45) | MEN1ALDH1A1KMT2ADRD2SLC6A4 | |
| SCHEMBL9428993 | 0.79 | ALDH1A1 (0.50) | MEN1ALDH1A1KMT2AHTR2ASIGMAR1 | |
| SCHEMBL9429307 | 0.79 | SIGMAR1 (0.58) | MEN1ALDH1A1KMT2ASIGMAR1HRH1 | |
| SCHEMBL9428246 | 0.79 | MEN1 (0.52) | MEN1ALDH1A1KMT2ADRD2HTR2A | |
| SCHEMBL9428716 | 0.79 | ALDH1A1 (0.52) | MEN1ALDH1A1KMT2ADRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332739-A | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-07-26 | — | — | US | disclosed |