Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9385499 | 0.85 | KCNH2 (0.46) | ALDH1A1SMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL9428865 | 0.79 | LMNA (0.36) | RXFP1ALDH1A1SMN1; SMN2KMT2ALMNA | |
| SCHEMBL9389044 | 0.78 | KCNH2 (0.46) | ALDH1A1SMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL9429247 | 0.77 | FDPS (0.40) | RXFP1ALDH1A1SMN1; SMN2KCNH2HRH1 | |
| SCHEMBL9429409 | 0.76 | FDPS (0.43) | ALDH1A1SMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL9429655 | 0.75 | ADRB2 (0.39) | RXFP1ALDH1A1SMN1; SMN2KCNH2TAAR1 | |
| SCHEMBL9428470 | 0.72 | CYP1A2 (0.62) | HTR1ARXFP1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL9429257 | 0.72 | MAPK1 (0.60) | RXFP1ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL10887423 | 0.71 | LMNA (0.43) | SMN1; SMN2LMNAKDM4EPOLBCYP1A2 | |
| SCHEMBL9383791 | 0.70 | MAPK1 (0.41) | ALDH1A1SMN1; SMN2MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332739-A | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-07-26 | — | — | US | disclosed |