Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | SLC47A2 | Q86VL8 | 1/20 | 0.38 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9428759 | 0.86 | ADRB2 (0.38) | ADRB2TAAR1RXFP1SIGMAR1SLC22A2 | |
| SCHEMBL9386225 | 0.84 | KCNH2 (0.55) | SIGMAR1SLC22A2ADRB1SLC6A4KCNH2 | |
| SCHEMBL9429247 | 0.84 | FDPS (0.40) | RXFP1SIGMAR1KCNH2ALDH1A1SMN1; SMN2 | |
| SCHEMBL9429025 | 0.82 | ADRB1 (0.36) | ADRB2TAAR1RXFP1SLC22A2ADRB1 | |
| SCHEMBL9436714 | 0.81 | SLC22A2 (0.43) | ADRB2TAAR1RXFP1SLC22A2ADRB1 | |
| SCHEMBL9428345 | 0.79 | SLC22A2 (0.40) | TAAR1RXFP1SIGMAR1SLC22A2ADRB1 | |
| SCHEMBL9428371 | 0.77 | TAAR1 (0.59) | ADRB2TAAR1RXFP1SLC22A2ADRB1 | |
| SCHEMBL9429918 | 0.77 | TAAR1 (0.59) | ADRB2TAAR1RXFP1SLC22A2ADRB1 | |
| SCHEMBL9429044 | 0.75 | HTR1A (0.37) | TAAR1RXFP1KCNH2ALDH1A1SMN1; SMN2 | |
| SCHEMBL9383791 | 0.74 | MAPK1 (0.41) | TAAR1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332739-A | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-07-26 | — | — | US | disclosed |