Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9429247 | 0.85 | FDPS (0.40) | FDPSMAOAMAOBSMN1; SMN2HRH3 | |
| SCHEMBL9387366 | 0.85 | KCNH2 (0.57) | MEN1KMT2ASMN1; SMN2HRH3KCNH2 | |
| SCHEMBL9429236 | 0.82 | MAOB (0.49) | L3MBTL1MAOBHRH3KDM4EALDH1A1 | |
| SCHEMBL9384775 | 0.81 | PKM (0.54) | SMN1; SMN2HRH3KCNH2PKM | |
| SCHEMBL9429044 | 0.76 | HTR1A (0.37) | MEN1TSHRKMT2ACYP1A2SMN1; SMN2 | |
| SCHEMBL9429706 | 0.72 | SLC6A4 (0.38) | FDPSMAOAMAOBCYP3A4SMN1; SMN2 | |
| SCHEMBL9428844 | 0.71 | HTR1A (0.35) | FDPSMEN1TSHRKMT2AMAOB | |
| SCHEMBL9429504 | 0.71 | THRB (0.39) | FDPSTSHRL3MBTL1MAOBCYP1A2 | |
| SCHEMBL3444885 | 0.71 | KDM4E (0.70) | MAOAMAOBCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL9384174 | 0.70 | KCNH2 (0.50) | CYP3A4SMN1; SMN2KCNH2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332739-A | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-07-26 | — | — | US | disclosed |