Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 13/20 | 0.46 |
| ▸ | HRH1 | P35367 | 8/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HRH2 | P25021 | 4/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9428874 | 0.92 | HRH1 (0.45) | HRH3HRH1HTR1AHTR2A | |
| SCHEMBL9429002 | 0.90 | HRH3 (0.45) | HRH3HRH1HRH2 | |
| SCHEMBL9428996 | 0.89 | HRH3 (0.41) | HRH3HRH1HTR1AHTR2AHRH2 | |
| SCHEMBL9428763 | 0.87 | KCNA5 (0.48) | HRH1HTR1A | |
| SCHEMBL9428911 | 0.85 | HRH1 (0.41) | HRH3HRH1HTR1AHTR2AHRH2 | |
| SCHEMBL9387106 | 0.84 | HTR1A (0.42) | HRH3HRH1HTR1AHTR2AHRH2 | |
| SCHEMBL9428459 | 0.82 | KCNA5 (0.41) | HRH3HRH1HTR1AHTR2AHRH2 | |
| SCHEMBL9428870 | 0.79 | HRH3 (0.57) | HRH3HRH1HRH2 | |
| SCHEMBL9429137 | 0.76 | HRH1 (0.39) | HRH3HRH1HTR1AHRH2 | |
| SCHEMBL9429616 | 0.76 | HRH3 (0.58) | HRH3HRH1HRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332739-A | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-07-26 | — | — | US | disclosed |