Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 13/20 | 0.58 |
| ▸ | HRH1 | P35367 | 12/20 | 0.51 |
| ▸ | HRH2 | P25021 | 9/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.44 |
| ▸ | IKBKB | O14920 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9428870 | 0.97 | HRH3 (0.57) | HRH3HRH1HRH2ALDH1A1MEN1 | |
| SCHEMBL9429336 | 0.86 | HRH3 (0.55) | HRH3MEN1KMT2ADRD2 | |
| SCHEMBL9430053 | 0.86 | ALDH1A1 (0.48) | HRH3HRH1ALDH1A1MEN1KMT2A | |
| SCHEMBL9428883 | 0.86 | HRH1 (0.50) | HRH3HRH1HRH2ALDH1A1MEN1 | |
| SCHEMBL9428808 | 0.85 | KCNJ1 (0.51) | HRH1ALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9429865 | 0.85 | HRH3 (0.54) | HRH3MEN1KMT2ADRD2 | |
| SCHEMBL9428835 | 0.83 | DRD2 (0.54) | HRH3HRH1HRH2ALDH1A1MEN1 | |
| SCHEMBL9429182 | 0.83 | HRH3 (0.64) | HRH3HRH1HRH2 | |
| SCHEMBL9429324 | 0.82 | DRD2 (0.56) | HRH3HRH1HRH2DRD2 | |
| SCHEMBL9428373 | 0.82 | DRD2 (0.58) | HRH3HRH1HRH2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332739-A | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-07-26 | — | — | US | disclosed |
| EP-0454498-A2 | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-10-30 | — | — | EP | disclosed |