Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 3/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HRH1 | P35367 | 5/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
| ▸ | HRH2 | P25021 | 2/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9428763 | 0.88 | KCNA5 (0.48) | KCNA5HTR1AHRH1DRD3 | |
| SCHEMBL9428911 | 0.86 | HRH1 (0.41) | HTR1AHTR2AHRH1PDGFRBHRH2 | |
| SCHEMBL9429465 | 0.84 | MAPT (0.52) | MEN1ALDH1A1KMT2AHTR1AHRH1 | |
| SCHEMBL9428874 | 0.84 | HRH1 (0.45) | KCNA5ALDH1A1HTR1AHTR2AHRH1 | |
| SCHEMBL9428996 | 0.83 | HRH3 (0.41) | HTR1AHTR2AHRH1HRH2HRH3 | |
| SCHEMBL9429396 | 0.82 | HRH3 (0.46) | HTR1AHTR2AHRH1HRH2HRH3 | |
| SCHEMBL9384119 | 0.82 | HTR1A (0.45) | MEN1ALDH1A1KMT2AHTR1AHTR2A | |
| SCHEMBL9429002 | 0.80 | HRH3 (0.45) | HRH1HRH2HRH3 | |
| Oxalic Acid SCHEMBL9388359 | 0.80 | ALDH1A1 (0.47) | MEN1ALDH1A1KMT2AHTR1AHTR2A | |
| SCHEMBL9429637 | 0.80 | HTR1A (0.48) | ALDH1A1HTR1AHTR2AHRH1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332739-A | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-07-26 | — | — | US | disclosed |
| EP-0454498-A2 | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-10-30 | — | — | EP | disclosed |