Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 14/20 | 0.50 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL9388465 | 0.82 | HTR7 (0.44) | HRH1ADRA1DADRA1AADRA1BHTR7 | |
| SCHEMBL9383082 | 0.82 | MAPT (0.48) | HRH1ADRA1DADRA1AADRA1BHTR7 | |
| SCHEMBL9428669 | 0.81 | HRH3 (0.64) | HRH1HRH3 | |
| SCHEMBL9429182 | 0.81 | HRH3 (0.64) | HRH1HRH3 | |
| SCHEMBL9429871 | 0.80 | HRH1 (0.48) | HRH1ADRA1DADRA1AADRA1BHTR7 | |
| SCHEMBL9428656 | 0.78 | ALDH1A1 (0.50) | HRH1ADRA1DADRA1AADRA1BMEN1 | |
| SCHEMBL9428377 | 0.78 | CCR5 (0.44) | HRH1ADRA1DADRA1AADRA1BMEN1 | |
| SCHEMBL9428772 | 0.78 | KDM4E (0.56) | HRH1ALDH1A1HRH3 | |
| SCHEMBL9428958 | 0.75 | HRH3 (0.47) | HRH1HRH3 | |
| SCHEMBL9428719 | 0.75 | HRH3 (0.47) | HRH1ALDH1A1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332739-A | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-07-26 | — | — | US | disclosed |
| EP-0454498-A2 | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-10-30 | — | — | EP | disclosed |