Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ACP3 | P15309 | 1/20 | 0.40 |
| ▸ | TLR4 | O00206 | 1/20 | 0.39 |
| ▸ | SRD5A1 | P18405 | 3/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16921278 | 0.73 | ADRA1A (0.38) | ADRA1ASRD5A1IDO1PDPK1SIGMAR1 | |
| SCHEMBL11718459 | 0.71 | TLR4 (0.68) | TLR4CYP19A1 | |
| SCHEMBL7118363 | 0.69 | ADRA1A (0.43) | ADRA1AIDO1PDPK1SIGMAR1 | |
| SCHEMBL133896 | 0.67 | HTR2A (0.49) | ADRA1AHTR2AIDO1PDPK1SIGMAR1 | |
| SCHEMBL3287343 | 0.67 | DDB1 (0.39) | ADRA1AACP3SRD5A1RETHTR2A | |
| SCHEMBL577658 | 0.66 | KDM1A (0.39) | IDO1PDPK1 | |
| SCHEMBL503849 | 0.66 | SIGMAR1 (0.62) | ADRA1AHTR2AGID4SIGMAR1 | |
| SCHEMBL29390302 | 0.66 | SIGMAR1 (0.62) | ADRA1AHTR2AGID4SIGMAR1 | |
| SCHEMBL775690 | 0.66 | KDM1A (0.35) | ADRA1AIDO1PDPK1 | |
| SCHEMBL3248949 | 0.66 | KDM1A (0.35) | ADRA1AIDO1PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5356935-A | Reductase inhibitors | ELI LILLY AND COMPANY (US) | 1994-10-18 | — | — | US | disclosed |