Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.35 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.35 |
| ▸ | ITGAL | P20701 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | CFTR | P13569 | 1/20 | 0.35 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3243868 | 0.82 | ITGB2 (0.48) | ABCG2ALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL6944653 | 0.78 | ALDH1A1 (0.40) | ALDH1A1KMT2ANPC1RAB9ASMN1; SMN2 | |
| Benzene SCHEMBL28224106 | 0.69 | ABCG2 (0.93) | ABCG2ALDH1A1PTGS2NPC1RAB9A | |
| SCHEMBL2697682 | 0.67 | — | — | |
| SCHEMBL22157876 | 0.66 | PTGS2 (0.51) | ABCG2ALDH1A1KMT2APTGS2PKM | |
| SCHEMBL8711 | 0.65 | — | — | |
| Biphenyl SCHEMBL1476554 | 0.65 | ALDH1A1 (0.64) | ALDH1A1NPC1RAB9ASMN1; SMN2MAPK1 | |
| Biphenyl SCHEMBL1950579 | 0.65 | ALDH1A1 (0.64) | ALDH1A1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4424499 | 0.65 | — | — | |
| Biphenyl SCHEMBL2548048 | 0.65 | ALDH1A1 (1.00) | ALDH1A1NPC1RAB9ASMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 428 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210100246-A1 | PYRIDYL-FORMAMIDINES HAVING A FUNGICIDAL ACTIVITY, THEIR AGRONOMIC COMPOSITIONS AND USE THEREOF | BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT | 2021-04-08 | — | — | US | claimed |
| WO-2016004028-A1 | 2-OXOPYRIMIDINE-5-CARBOXYLATE DERIVATIVES FOR TREATING THYROID DISEASES | LATIF RAUF (US) | 2016-01-07 | — | — | WO | claimed |
| US-8471024-B2 | Tetrahydrofuropyridones | MERCK SHARP & DOHME, CORP. (US) | 2013-06-25 | — | — | US | claimed |
| EP-2257169-B1 | TETRAHYDROTHIENO PYRIDINES | MERCK SHARP & DOHME (US) | 2013-06-05 | — | — | EP | claimed |
| US-8445680-B2 | Tetrahydrothieno pyridines | MERCK SHARP & DOHME CORP. (US) | 2013-05-21 | — | — | US | claimed |
| EP-2257170-B1 | TETRAHYDROFUROPYRIDONES | MERCK SHARP & DOHME (US) | 2012-12-26 | — | — | EP | claimed |
| CN-101117328-B | Fatty acid synthetase inhibitor and application for treating bacterial infection | INST PHARM & TOXICOLOGY AMMS | 2012-11-07 | — | — | CN | claimed |
| WO-2011032159-A1 | METHODS TO PREVENT A HAIR-RELATED SIDE EFFECT OF TREATMENT WITH A CHEMOTHERAPEUTIC AGENT | META COMESTICS, LLC (US) | 2011-03-17 | — | — | WO | claimed |
| CN-101951777-A | Tetrahydrofuropyridones | MERCK & CO INC | 2011-01-19 | — | — | CN | claimed |
| US-20110009425-A1 | TETRAHYDROTHIENO PYRIDINES | MERCK SHARP & DOHME LLC | 2011-01-13 | — | — | US | claimed |
| CN-1009093-B | Process for producing ketene S, S-acetal derivative | NIHON NOHYAKU CO LTD (JP) | 1990-08-08 | — | — | CN | claimed |
| US-4738976-A | Antimycotic agent and fungicidal agent | NIHON NOHYAKU CO., LTD. (JP) | 1988-04-19 | — | — | US | claimed |
| EP-0218736-A1 | A ketene S,S-acetal derivative, a process for manufacturing thereof and a method for curing mycosis by administering it | NIHON NOHYAKU CO., LTD. (JP) | 1987-04-22 | — | — | EP | claimed |
| CN-85109322-A | New ketene S, the manufacture method of S-acetal derivatives and treat mycotic method | — | 1987-04-15 | — | — | CN | claimed |
| US-4636519-A | FUNGICIDE | NIHON NOHYAKU CO., LTD. (JP) | 1987-01-13 | — | — | US | claimed |
| US-4598086-A | ANTIDERPRESSANTS; HYPERTENSIVE AGENTS | SYNTHELABO, (FR) | 1986-07-01 | — | — | US | claimed |
| EP-0023559-B1 | 2-(PERHYDRO-1,4-DIAZINO)-PYRIMIDO(5,4-D)PYRIMIDINES, THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | Dr. Karl Thomae GmbH (DE) | 1984-09-19 | — | — | EP | claimed |
| EP-0005783-B1 | IMIDAZO (2.1-B)-(1.3.4)-THIADIAZOLES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN MEDICAMENTS | BAYER AG (DE) | 1981-12-30 | — | — | EP | claimed |
| EP-0023559-A1 | 2-(Perhydro-1,4-diazino)-pyrimido(5,4-d)pyrimidines, their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1981-02-11 | — | — | EP | claimed |
| US-4213984-A | ANTIULCER AGENTS, ANTISECRETORY AGENTS | BOEHRINGER INGELHEIM GMBH (DE) | 1980-07-22 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110009425-A1 | TETRAHYDROTHIENO PYRIDINES | HIF1AN, HIF1A, EGLN3 | ABCG2 4417/4885ALDH1A1 691/4885KMT2A 333/4885 |
| US-20210100246-A1 | PYRIDYL-FORMAMIDINES HAVING A FUNGICIDAL ACTIVITY, THEIR AGRONOMIC COMPOSITIONS AND USE THEREOF | PFAS, PNPO, PGM2 | ABCG2 655/4885ALDH1A1 1216/4885KMT2A 1474/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.