Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 5/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | PRNP | P04156 | 5/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL943064 | 0.72 | ALDH1A1 (0.71) | HSD17B10ALDH1A1RXFP1MAPK1HPGD | |
| SCHEMBL9432046 | 0.69 | ERN1 (0.39) | POLBALDH1A1MAPK1HPGDNPSR1 | |
| SCHEMBL5278158 | 0.68 | ANPEP (0.64) | HSD17B10POLBALDH1A1RXFP1MAPK1 | |
| SCHEMBL28702281 | 0.68 | ALDH1A1 (0.63) | HSD17B10POLBALDH1A1RXFP1HPGD | |
| SCHEMBL3780489 | 0.68 | ALDH1A1 (0.56) | POLBALDH1A1HPGDL3MBTL1GAA | |
| SCHEMBL8144828 | 0.67 | HSD17B10 (0.66) | HSD17B10POLBALDH1A1RXFP1MAPK1 | |
| SCHEMBL5963190 | 0.67 | ALDH1A1 (0.52) | ALDH1A1HPGDALOX15NPSR1TSHR | |
| SCHEMBL29678864 | 0.67 | ALDH1A1 (0.52) | ALDH1A1HPGDALOX15NPSR1TSHR | |
| SCHEMBL9999239 | 0.67 | STAT3 (0.67) | HSD17B10POLBMAPTCYP1A2CYP3A4 | |
| SCHEMBL11544945 | 0.66 | HSD17B10 (0.64) | HSD17B10POLBALDH1A1RXFP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5340833-A | Antiarthritic, antiinflammatory, antitumor agents | EISAI CO., LTD. (JP) | 1994-08-23 | — | — | US | disclosed |
| EP-0568289-A2 | Benzothiophenes and thienothiophenes and related compounds useful, for example, as urokinase inhibitors | Eisai Co., Ltd. (JP) | 1993-11-03 | — | — | EP | disclosed |