Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | TACR3 | P29371 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | EDNRA | P25101 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9432049 | 0.69 | HSD17B10 (0.48) | KMT2AALDH1A1HPGDKDM4ENPSR1 | |
| SCHEMBL29678864 | 0.68 | ALDH1A1 (0.52) | ERN1KMT2AALDH1A1HPGDNPSR1 | |
| SCHEMBL5963190 | 0.68 | ALDH1A1 (0.52) | ERN1KMT2AALDH1A1HPGDNPSR1 | |
| SCHEMBL29951294 | 0.67 | CYP1A2 (0.57) | ERN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL6362144 | 0.67 | CYP1A2 (0.57) | ERN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL16548172 | 0.67 | SLC6A3 (0.47) | ERN1KMT2ATACR3ALDH1A1HPGD | |
| SCHEMBL11467663 | 0.66 | KMT2A (0.45) | KMT2AALDH1A1HPGDLMNAMAPK1 | |
| 2-Naphthaldehyde SCHEMBL9383019 | 0.66 | RECQL (0.43) | MAPT | |
| SCHEMBL6200530 | 0.66 | NQO2 (0.55) | ERN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL28139963 | 0.66 | CYP2A6 (0.39) | ERN1KMT2AALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5340833-A | Antiarthritic, antiinflammatory, antitumor agents | EISAI CO., LTD. (JP) | 1994-08-23 | — | — | US | disclosed |
| EP-0568289-A2 | Benzothiophenes and thienothiophenes and related compounds useful, for example, as urokinase inhibitors | Eisai Co., Ltd. (JP) | 1993-11-03 | — | — | EP | disclosed |