Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | JUN | P05412 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.45 |
| ▸ | GPR183 | P32249 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9433826 | 0.87 | TBXAS1 (0.57) | TBXAS1THRBNAPRTPOLBKMT2A | |
| SCHEMBL9433920 | 0.87 | TBXAS1 (0.56) | TBXAS1THRBNAPRTPOLBKMT2A | |
| SCHEMBL9433523 | 0.86 | TBXAS1 (0.56) | TBXAS1THRBNAPRTPOLBKMT2A | |
| SCHEMBL9434018 | 0.86 | TBXAS1 (0.56) | TBXAS1THRBNAPRTPOLBKMT2A | |
| SCHEMBL9434440 | 0.85 | LMNA (0.47) | TBXAS1THRBNAPRTPOLBKMT2A | |
| SCHEMBL9434294 | 0.83 | MAPT (0.63) | TBXAS1THRBNAPRTPOLBRAB9A | |
| SCHEMBL9433343 | 0.83 | TBXAS1 (0.52) | TBXAS1THRBNAPRTPOLBKMT2A | |
| SCHEMBL9433645 | 0.82 | MAPT (0.69) | TBXAS1POLBRAB9AMAPTHTT | |
| SCHEMBL9434179 | 0.80 | GSK3B (0.68) | TBXAS1THRBKMT2ARAB9AKDM4E | |
| SCHEMBL9434498 | 0.80 | NAPRT (0.49) | TBXAS1NAPRTKMT2AMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276150-A | Vasodilators, anticoagulants, calcium channel blockers | FUJIREBIO INC. (JP) | 1994-01-04 | — | — | US | disclosed |
| EP-0400660-A1 | 1,4-dihydropyridine derivatives | FUJIREBIO INC. (JP) | 1990-12-05 | — | — | EP | disclosed |