Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.52 |
| ▸ | SNCA | P37840 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | P4HB | P07237 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9434552 | 0.86 | P4HB (0.48) | MAPTALDH1A1TBXAS1LMNANAPRT | |
| SCHEMBL9433826 | 0.84 | TBXAS1 (0.57) | MAPTTBXAS1HTTNAPRTPOLB | |
| SCHEMBL9433920 | 0.84 | TBXAS1 (0.56) | MAPTTBXAS1HTTNAPRTPOLB | |
| SCHEMBL9434018 | 0.83 | TBXAS1 (0.56) | MAPTTBXAS1HTTLMNANAPRT | |
| SCHEMBL9433523 | 0.83 | TBXAS1 (0.56) | MAPTTBXAS1HTTNAPRTPOLB | |
| SCHEMBL9433504 | 0.83 | TBXAS1 (0.56) | MAPTALDH1A1TBXAS1HTTNAPRT | |
| SCHEMBL9433343 | 0.80 | TBXAS1 (0.52) | MAPTTBXAS1HTTNAPRTPOLB | |
| SCHEMBL9434179 | 0.79 | GSK3B (0.68) | MAPTALDH1A1TBXAS1LMNATHRB | |
| SCHEMBL9433645 | 0.79 | MAPT (0.69) | MAPTALDH1A1TBXAS1HTTLMNA | |
| SCHEMBL9433528 | 0.79 | NAPRT (0.46) | MAPTALDH1A1TBXAS1LMNANAPRT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276150-A | Vasodilators, anticoagulants, calcium channel blockers | FUJIREBIO INC. (JP) | 1994-01-04 | — | — | US | disclosed |
| EP-0400660-A1 | 1,4-dihydropyridine derivatives | FUJIREBIO INC. (JP) | 1990-12-05 | — | — | EP | disclosed |