Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.69 |
| ▸ | HTT | P42858 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.51 |
| ▸ | NAMPT | P43490 | 1/20 | 0.51 |
| ▸ | TGM2 | P21980 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7382581 | 0.87 | TGM2 (0.66) | MAPTHTTALDH1A1LMNANPC1 | |
| SCHEMBL9433826 | 0.83 | TBXAS1 (0.57) | MAPTHTTPOLBNPC1RAB9A | |
| SCHEMBL9433920 | 0.83 | TBXAS1 (0.56) | MAPTHTTPOLBNPC1RAB9A | |
| SCHEMBL9433523 | 0.82 | TBXAS1 (0.56) | MAPTHTTPOLBNPC1RAB9A | |
| SCHEMBL9433504 | 0.82 | TBXAS1 (0.56) | MAPTHTTALDH1A1POLBNPC1 | |
| SCHEMBL9434018 | 0.82 | TBXAS1 (0.56) | MAPTHTTLMNAPOLBNPC1 | |
| SCHEMBL9433587 | 0.79 | ALDH1A1 (0.61) | MAPTHTTALDH1A1LMNANPC1 | |
| SCHEMBL9434294 | 0.79 | MAPT (0.63) | MAPTHTTALDH1A1LMNAPOLB | |
| SCHEMBL9433343 | 0.79 | TBXAS1 (0.52) | MAPTHTTPOLBNPC1RAB9A | |
| SCHEMBL3014843 | 0.78 | MAPT (1.00) | MAPTHTTALDH1A1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276150-A | Vasodilators, anticoagulants, calcium channel blockers | FUJIREBIO INC. (JP) | 1994-01-04 | — | — | US | disclosed |
| EP-0400660-A1 | 1,4-dihydropyridine derivatives | FUJIREBIO INC. (JP) | 1990-12-05 | — | — | EP | disclosed |