Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 4/20 | 0.56 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.46 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.46 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.46 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9433826 | 0.87 | TBXAS1 (0.57) | TBXAS1NAPRTPOLBTHRBKMT2A | |
| SCHEMBL9433920 | 0.87 | TBXAS1 (0.56) | TBXAS1NAPRTPOLBTHRBMEN1 | |
| SCHEMBL9433504 | 0.86 | TBXAS1 (0.56) | TBXAS1NAPRTPOLBTHRBMEN1 | |
| SCHEMBL9433523 | 0.86 | TBXAS1 (0.56) | TBXAS1NAPRTPOLBTHRBMEN1 | |
| SCHEMBL9434693 | 0.85 | CYP1A2 (0.56) | TBXAS1NAPRTTHRBKMT2AMAPT | |
| SCHEMBL9434294 | 0.83 | MAPT (0.63) | TBXAS1NAPRTPOLBTHRBMAPT | |
| SCHEMBL9433343 | 0.83 | TBXAS1 (0.52) | TBXAS1NAPRTPOLBTHRBMEN1 | |
| SCHEMBL9433645 | 0.82 | MAPT (0.69) | TBXAS1POLBMAPTHTTLMNA | |
| SCHEMBL9434179 | 0.80 | GSK3B (0.68) | TBXAS1THRBMEN1KMT2AMAPT | |
| SCHEMBL9433802 | 0.80 | NAPRT (0.49) | TBXAS1NAPRTPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276150-A | Vasodilators, anticoagulants, calcium channel blockers | FUJIREBIO INC. (JP) | 1994-01-04 | — | — | US | disclosed |
| EP-0400660-A1 | 1,4-dihydropyridine derivatives | FUJIREBIO INC. (JP) | 1990-12-05 | — | — | EP | disclosed |