Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | BACE1 | P56817 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 8/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.46 |
| ▸ | P4HB | P07237 | 1/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.46 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | FDPS | P14324 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9434718 | 0.82 | NAPRT (0.50) | NFKB1NFE2L2NAPRTCYP1A2CYP3A4 | |
| SCHEMBL9433617 | 0.81 | HSD11B1 (0.50) | NAPRTCYP1A2CYP3A4CYP2C9LMNA | |
| SCHEMBL9433799 | 0.81 | MAPT (0.61) | MAOBNAPRTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9434498 | 0.81 | NAPRT (0.49) | NAPRTCYP1A2CYP3A4CYP2C9LMNA | |
| SCHEMBL9433573 | 0.81 | NAPRT (0.49) | NAPRTCYP1A2CYP3A4CYP2C9LMNA | |
| SCHEMBL9434607 | 0.79 | CYP1A2 (0.53) | BACE1NAPRTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9433343 | 0.79 | TBXAS1 (0.52) | MAOBP4HBNAPRTCYP1A2CYP3A4 | |
| SCHEMBL9433528 | 0.78 | NAPRT (0.46) | NAPRTCYP1A2CYP3A4CYP2C9LMNA | |
| SCHEMBL9433587 | 0.77 | ALDH1A1 (0.61) | NFKB1BACE1MAOBLMNAMEN1 | |
| SCHEMBL9434583 | 0.76 | KMT2A (0.49) | NAPRTCYP1A2CYP3A4CYP2C9LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276150-A | Vasodilators, anticoagulants, calcium channel blockers | FUJIREBIO INC. (JP) | 1994-01-04 | — | — | US | disclosed |
| EP-0400660-A1 | 1,4-dihydropyridine derivatives | FUJIREBIO INC. (JP) | 1990-12-05 | — | — | EP | disclosed |