Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9434718 | 0.85 | NAPRT (0.50) | NAPRTCYP1A2CYP3A4CYP2C9HDAC3 | |
| SCHEMBL9433799 | 0.84 | MAPT (0.61) | NAPRTCYP1A2CYP3A4CYP2C9HDAC1 | |
| SCHEMBL9433617 | 0.84 | HSD11B1 (0.50) | NAPRTCYP1A2CYP3A4CYP2C9HDAC3 | |
| SCHEMBL9434498 | 0.84 | NAPRT (0.49) | NAPRTCYP1A2CYP3A4CYP2C9HDAC3 | |
| SCHEMBL9434607 | 0.82 | CYP1A2 (0.53) | NAPRTCYP1A2CYP3A4CYP2C9HDAC8 | |
| SCHEMBL9433528 | 0.81 | NAPRT (0.46) | NAPRTCYP1A2CYP3A4CYP2C9HDAC3 | |
| SCHEMBL9433558 | 0.81 | NFKB1 (0.54) | NAPRTCYP1A2CYP3A4CYP2C9LMNA | |
| SCHEMBL9433587 | 0.80 | ALDH1A1 (0.61) | ALDH1A1LMNAMAPTKMT2ANPC1 | |
| SCHEMBL9433523 | 0.80 | TBXAS1 (0.56) | NAPRTCYP1A2CYP3A4CYP2C9HDAC3 | |
| SCHEMBL9434583 | 0.79 | KMT2A (0.49) | NAPRTCYP1A2CYP3A4CYP2C9HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276150-A | Vasodilators, anticoagulants, calcium channel blockers | FUJIREBIO INC. (JP) | 1994-01-04 | — | — | US | disclosed |
| EP-0400660-A1 | 1,4-dihydropyridine derivatives | FUJIREBIO INC. (JP) | 1990-12-05 | — | — | EP | disclosed |