Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.61 |
| ▸ | MAPT | P10636 | 6/20 | 0.61 |
| ▸ | RAB9A | P51151 | 5/20 | 0.61 |
| ▸ | NPC1 | O15118 | 4/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | BACE1 | P56817 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9433799 | 0.82 | MAPT (0.61) | ALDH1A1MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL9434718 | 0.81 | NAPRT (0.50) | ALDH1A1MAPTRAB9ANPC1MEN1 | |
| SCHEMBL9434498 | 0.80 | NAPRT (0.49) | ALDH1A1MAPTHTTKMT2ALMNA | |
| SCHEMBL9433573 | 0.80 | NAPRT (0.49) | ALDH1A1MAPTRAB9ANPC1KMT2A | |
| SCHEMBL9433617 | 0.80 | HSD11B1 (0.50) | ALDH1A1MAPTRAB9ANPC1KMT2A | |
| SCHEMBL9433645 | 0.79 | MAPT (0.69) | ALDH1A1MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7382581 | 0.79 | TGM2 (0.66) | ALDH1A1MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL9434607 | 0.78 | CYP1A2 (0.53) | ALDH1A1MAPTSMN1; SMN2BACE1LMNA | |
| SCHEMBL9433558 | 0.77 | NFKB1 (0.54) | MAPTBACE1MAOBMEN1KMT2A | |
| SCHEMBL9433528 | 0.77 | NAPRT (0.46) | ALDH1A1MAPTRAB9ANPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276150-A | Vasodilators, anticoagulants, calcium channel blockers | FUJIREBIO INC. (JP) | 1994-01-04 | — | — | US | disclosed |
| EP-0400660-A1 | 1,4-dihydropyridine derivatives | FUJIREBIO INC. (JP) | 1990-12-05 | — | — | EP | disclosed |