SCHEMBL943365

SCHEMBL943365

C=CC(=O)NCC(C)(C)C=O

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.48
ALDH1A1 P00352 3/20 0.48
MAPK1 P28482 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
ZDHHC20 Q5W0Z9 1/20 0.41
ZDHHC2 Q9UIJ5 1/20 0.41
GAA P10253 1/20 0.36
CYP3A4 P08684 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
TGM2 P21980 2/20 0.34
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
CNR1 P21554 4/20 0.30
CNR2 P34972 4/20 0.30
LMNA P02545 1/20 0.30
TP53 P04637 1/20 0.30
TRPA1 O75762 1/20 0.30
TRPV1 Q8NER1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9763131 0.88 ALDH1A1 (0.38) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL138083 0.80 ALDH1A1 (0.54) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL4789482 0.80 TSHR (0.54) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL23064184 0.78 ALDH1A1 (0.52) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL6566267 0.78 ALDH1A1 (0.52) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL2426544 0.78 L3MBTL1 (0.31) TSHRALDH1A1MAPK1CYP3A4MEN1
SCHEMBL6656224 0.77 ALDH1A1 (0.50) TSHRALDH1A1MAPK1TDP1ZDHHC20
Dimethylamine SCHEMBL9134759 0.77 ALDH1A1 (0.50) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL19069377 0.77 ALDH1A1 (0.50) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL27401811 0.77 ALDH1A1 (0.50) TSHRALDH1A1MAPK1TDP1ZDHHC20

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110196084-A1 AQUEOUS CROSSLINKABLE VINYL GRAFT COPOLYMER COMPOSITIONS DSM IP ASSETS B.V. (NL) 2011-08-11 US claimed
EP-2032648-A1 AQUEOUS CROSSLINKABLE VINYL GRAFT COPOLYMER COMPOSITIONS DSMIP Assets B.V. (NL) 2009-03-11 EP claimed
WO-2007147561-A1 AQUEOUS CROSSLINKABLE VINYL GRAFT COPOLYMER COMPOSITIONS DSM IP ASSETS B.V. (NL) 2007-12-27 WO claimed
EP-3935113-B1 AQUEOUS COATING COMPOSITION ALLNEX NETHERLANDS BV (NL) 2026-05-06 EP disclosed
US-12595384-B1 Polymer latex for matte films SWIMC LLC (US) 2026-04-07 US disclosed
US-12565542-B2 Waterborne coating composition ALLNEX NETHERLANDS BV (NL) 2026-03-03 US disclosed
US-12534634-B2 Aqueous coating composition ALLNEX NETHERLANDS (NL) 2026-01-27 US disclosed
EP-3856703-B1 POLYAMINE ADDITIVE LUBRIZOL ADVANCED MAT INC (US) 2025-08-27 EP disclosed
EP-4367151-B1 AQUEOUS VINYL POLYMER DISPERSION ALLNEX NETHERLANDS BV (NL) 2025-07-16 EP disclosed
WO-2025098970-A1 WATERBORNE COATING COMPOSITION ALLNEX NETHERLANDS B.V. (NL) 2025-05-15 WO disclosed
US-12240941-B2 Rosin-based polymer for stain-blocking coating compositions SWIMC LLC (US) 2025-03-04 US disclosed
US-4952623-A ADDITION POLYMERS CROSSLINKED WITH DIHYDRAZIDES BASF AKTIENGESELLSCHAFT (DE) 1990-08-28 US disclosed
US-4931494-A Aqueous polymer dispersions having a long shelf life BASF AKTIENGESELLSCHAFT (DE) 1990-06-05 US disclosed
US-4904724-A FREE RADICAL POLYMERIZATION OF CI-C20-ALKYL(METH)ACRYLATE AND UNSATURATED MONOMERS BASF AKTIENGESELLSCHAFT (DE) 1990-02-27 US disclosed
US-4894261-A Production of a multilayer coating BASF AKTIENGESELLSCHAFT (DE) 1990-01-16 US disclosed
EP-0341886-A2 Aqueous coating compositions ZENECA RESINS BV (NL) 1989-11-15 EP disclosed
EP-0332326-A2 Polyurethane coating compositions ICI RESINS BV (NL) 1989-09-13 EP disclosed
US-4786676-A CARBONYL CONTAINING POLYMERS REACTED WITH POLYHYDRAZIDE BASF AKTIENGESELLSCHAFT (DE) 1988-11-22 US disclosed
US-4769410-A Crosslinkable compositions dissolved or dispersed in an organic solvent and having a long shelf life, their preparation and their use BASF AKTIENGESELLSCHAFT (DE) 1988-09-06 US disclosed
US-4250070-A ALSO CONTAINING HEAVY METAL IONS; STORAGE STABILITY; CROSSLINKING; COATINGS BASF AKTIENGESELLSCHAFT (DE) 1981-02-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12595384-B1 Polymer latex for matte films TERT, MYD88, MACF1 TSHR 2154/4885ALDH1A1 1501/4885MAPK1 2255/4885
US-12565542-B2 Waterborne coating composition CHRM1, CHRM2, CCNT1 TSHR 4267/4885ALDH1A1 920/4885MAPK1 3689/4885
US-12534634-B2 Aqueous coating composition CHRM1, CD274, CHRM2 TSHR 2979/4885ALDH1A1 839/4885MAPK1 2736/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.