Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | NAMPT | P43490 | 2/20 | 0.46 |
| ▸ | FNTA | P49354 | 1/20 | 0.45 |
| ▸ | FNTB | P49356 | 1/20 | 0.45 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.45 |
| ▸ | CYP21A2 | P08686 | 1/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9433920 | 0.83 | TBXAS1 (0.56) | NAPRTMEN1KMT2ATBXAS1CYP1A2 | |
| SCHEMBL9433826 | 0.81 | TBXAS1 (0.57) | NAPRTKMT2ATBXAS1CYP1A2CYP3A4 | |
| SCHEMBL9434748 | 0.80 | CYP1A1 (0.62) | NAPRTKMT2ATBXAS1CYP1A2CYP1A1 | |
| SCHEMBL9433523 | 0.80 | TBXAS1 (0.56) | NAPRTMEN1KMT2ATBXAS1CYP1A2 | |
| SCHEMBL9434096 | 0.80 | NAPRT (0.50) | NAPRTMEN1KMT2ATBXAS1CYP1A2 | |
| SCHEMBL9433504 | 0.80 | TBXAS1 (0.56) | NAPRTMEN1KMT2ATBXAS1CYP1A2 | |
| SCHEMBL9434018 | 0.80 | TBXAS1 (0.56) | NAPRTMEN1KMT2ATBXAS1CYP1A2 | |
| SCHEMBL9434693 | 0.79 | CYP1A2 (0.56) | NAPRTKMT2ATBXAS1CYP1A2CYP3A4 | |
| SCHEMBL9433864 | 0.79 | NAPRT (0.47) | NAPRTTBXAS1CYP1A2CYP3A4CYP1A1 | |
| SCHEMBL9434440 | 0.79 | LMNA (0.47) | NAPRTMEN1KMT2ATBXAS1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276150-A | Vasodilators, anticoagulants, calcium channel blockers | FUJIREBIO INC. (JP) | 1994-01-04 | — | — | US | disclosed |
| EP-0400660-A1 | 1,4-dihydropyridine derivatives | FUJIREBIO INC. (JP) | 1990-12-05 | — | — | EP | disclosed |