Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.57 |
| ▸ | TTR | P02766 | 1/20 | 0.57 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13704177 | 0.85 | HTR1A (0.74) | SMN1; SMN2KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL29555131 | 0.83 | KMT2A (0.59) | SMN1; SMN2KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL10037013 | 0.83 | KMT2A (0.59) | SMN1; SMN2KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL689212 | 0.83 | KMT2A (0.59) | SMN1; SMN2KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL20024204 | 0.81 | LMNA (0.56) | SMN1; SMN2KMT2AALDH1A1HPGDMAPT | |
| SCHEMBL17576048 | 0.81 | LMNA (0.56) | SMN1; SMN2KMT2AALDH1A1HPGDMAPT | |
| SCHEMBL20031124 | 0.80 | CA12 (0.57) | KMT2AMAPTLMNARAB9AMEN1 | |
| Methyl Cis-3,4-Dimethoxycinnamate SCHEMBL2411956 | 0.79 | FDPS (0.80) | SMN1; SMN2KMT2AKDM4EALDH1A1HPGD | |
| Methyl Cis-3,4-Dimethoxycinnamate SCHEMBL2411955 | 0.79 | FDPS (0.80) | SMN1; SMN2KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL14982038 | 0.79 | NFKB1 (0.68) | SMN1; SMN2KMT2AKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5369106-A | N-acryloylpiperazine derivatives, their preparation and their use of PAF antagonists | SANKYO COMPANY, LIMITED (JP) | 1994-11-29 | — | — | US | disclosed |