SCHEMBL689212

SCHEMBL689212

COc1ccc(C=CC(=O)Oc2ccccc2C)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.59
MEN1 O00255 2/20 0.59
MAPT P10636 2/20 0.59
F3 P13726 2/20 0.55
BCHE P06276 1/20 0.55
CYP3A4 P08684 1/20 0.55
NFKB1 P19838 1/20 0.55
NFKB2 Q00653 1/20 0.55
RELA Q04206 1/20 0.55
ATM Q13315 2/20 0.55
TDP1 Q9NUW8 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
KDM4E B2RXH2 2/20 0.54
THRB P10828 1/20 0.54
SMN1; SMN2 Q16637 2/20 0.53
ALDH1A1 P00352 2/20 0.53
GSK3B P49841 1/20 0.53
HDAC3 O15379 1/20 0.51
HDAC1 Q13547 1/20 0.51
HDAC2 Q92769 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10037013 1.00 KMT2A (0.59) KMT2AMEN1MAPTF3BCHE
SCHEMBL29555131 1.00 KMT2A (0.59) KMT2AMEN1MAPTF3BCHE
SCHEMBL20024204 0.87 LMNA (0.56) KMT2AMEN1MAPTCYP3A4L3MBTL1
SCHEMBL17576048 0.87 LMNA (0.56) KMT2AMEN1MAPTCYP3A4L3MBTL1
SCHEMBL17304586 0.86 KMT2A (0.67) KMT2AMEN1MAPTF3ATM
SCHEMBL20031124 0.85 CA12 (0.57) KMT2AMEN1MAPTF3BCHE
SCHEMBL12010094 0.85 KMT2A (0.58) KMT2AMEN1MAPTRELAKDM4E
SCHEMBL688718 0.85 KMT2A (0.58) KMT2AMEN1MAPTRELAKDM4E
SCHEMBL28113537 0.84 KMT2A (0.58) KMT2AMEN1MAPTF3BCHE
SCHEMBL9434133 0.83 SMN1; SMN2 (0.68) KMT2AMEN1MAPTKDM4ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4691452-A1 COSMETIC COMPOSITION Shiseido Company, Ltd. (JP) 2026-02-11 EP claimed
WO-2024203340-A1 COSMETIC COMPOSITION 株式会社 資生堂 2024-10-03 WO claimed
WO-2024202309-A1 COSMETIC COMPOSITION 株式会社 資生堂 2024-10-03 WO claimed
CN-107913194-B Ultraviolet radiation absorbing polymer composition 强生消费者公司 2022-06-28 CN claimed
EP-4691452-A1 COSMETIC COMPOSITION Shiseido Company, Ltd. (JP) 2026-02-11 EP disclosed
EP-4691453-A1 COSMETIC COMPOSITION Shiseido Company, Ltd. (JP) 2026-02-11 EP disclosed
WO-2024203341-A1 COSMETIC COMPOSITION 株式会社 資生堂 2024-10-03 WO disclosed
WO-2024203340-A1 COSMETIC COMPOSITION 株式会社 資生堂 2024-10-03 WO disclosed
WO-2024202309-A1 COSMETIC COMPOSITION 株式会社 資生堂 2024-10-03 WO disclosed
WO-2023149245-A1 WATER-IN-OIL EMULSION COSMETIC 株式会社 資生堂 2023-08-10 WO disclosed
CN-107913194-B Ultraviolet radiation absorbing polymer composition 强生消费者公司 2022-06-28 CN disclosed
CN-109790286-B Ultraviolet radiation absorbing polymer composition 巴斯夫欧洲公司 2022-04-12 CN disclosed
CN-106163492-B Cosmetic UV absorber mixture 巴斯夫欧洲公司 2019-12-13 CN disclosed
US-20180200170-A1 SUNSCREEN FORMULATIONS OPTIMIZED FOR THE FORMATION OF VITAMIN D UV-TECHNIK (DE) 2018-07-19 US disclosed
US-20160067158-A1 AGENTS CONTAINING LARGE QUANTITIES OF UV STABILIZERS BASF SE (DE) 2016-03-10 US disclosed
US-8252273-B2 Ultraviolet absorber LEAD CHEMICAL CO., LTD. (JP) 2012-08-28 US disclosed
EP-2192106-B1 ULTRAVIOLET ABSORBER LEAD CHEM CO LTD (JP) 2012-02-29 EP disclosed
US-20100239508-A1 ULTRAVIOLET ABSORBER LEAD CHEMICAL CO., LTD. (JP) 2010-09-23 US disclosed
EP-2192106-A1 ULTRAVIOLET ABSORBER Lead Chemical Co. Ltd. (JP) 2010-06-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160067158-A1 AGENTS CONTAINING LARGE QUANTITIES OF UV STABILIZERS ERCC5, ERCC1, TTPA KMT2A 3804/4885MEN1 4242/4885MAPT 425/4885
US-20100239508-A1 ULTRAVIOLET ABSORBER UNG, UACA, ABCG2 KMT2A 4596/4885MEN1 3021/4885MAPT 564/4885
US-20180200170-A1 SUNSCREEN FORMULATIONS OPTIMIZED FOR THE FORMATION OF VITAMIN D VDR, CYP2R1, CYP24A1 KMT2A 4636/4885MEN1 1547/4885MAPT 2601/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.