Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9434729 | 0.86 | MAOA (0.36) | GPBAR1 | |
| SCHEMBL9433807 | 0.85 | LIMK1 (0.41) | GPBAR1 | |
| SCHEMBL9433625 | 0.85 | KMT2A (0.35) | GPBAR1 | |
| SCHEMBL9433586 | 0.85 | MAOA (0.35) | GPBAR1TACR1 | |
| SCHEMBL9434522 | 0.83 | SLC22A12 (0.44) | — | |
| SCHEMBL9433534 | 0.82 | GPBAR1 (0.42) | GPBAR1 | |
| SCHEMBL9433598 | 0.81 | RORC (0.40) | — | |
| SCHEMBL9433512 | 0.81 | SLC22A12 (0.41) | GPBAR1 | |
| SCHEMBL9434595 | 0.80 | MEN1 (0.38) | — | |
| SCHEMBL9433711 | 0.80 | SLC22A12 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276150-A | Vasodilators, anticoagulants, calcium channel blockers | FUJIREBIO INC. (JP) | 1994-01-04 | — | — | US | disclosed |
| EP-0400660-A1 | 1,4-dihydropyridine derivatives | FUJIREBIO INC. (JP) | 1990-12-05 | — | — | EP | disclosed |