Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 9/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | FBP1 | P09467 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9434826 | 1.00 | L3MBTL1 (0.56) | L3MBTL1MAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL9434339 | 0.84 | GLO1 (0.63) | L3MBTL1MAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL9434342 | 0.84 | GLO1 (0.63) | L3MBTL1MAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL5698531 | 0.79 | AKR1C3 (0.49) | L3MBTL1MAPTRAB9AALDH1A1MAPK1 | |
| SCHEMBL5698524 | 0.79 | AKR1C3 (0.49) | L3MBTL1MAPTRAB9AALDH1A1MAPK1 | |
| SCHEMBL5253681 | 0.79 | AKR1C1 (0.55) | MAPTALDH1A1MAPK1POLBMEN1 | |
| SCHEMBL5253679 | 0.79 | AKR1C1 (0.55) | MAPTALDH1A1MAPK1POLBMEN1 | |
| SCHEMBL9433771 | 0.77 | RAB9A (0.62) | L3MBTL1MAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL9433640 | 0.77 | RAB9A (0.62) | L3MBTL1MAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL5698449 | 0.77 | MPO (0.53) | MAPTRAB9ANPC1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276150-A | Vasodilators, anticoagulants, calcium channel blockers | FUJIREBIO INC. (JP) | 1994-01-04 | — | — | US | disclosed |
| EP-0400660-A1 | 1,4-dihydropyridine derivatives | FUJIREBIO INC. (JP) | 1990-12-05 | — | — | EP | disclosed |