Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ACLY | P53396 | 13/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9436621 | 0.84 | LMNA (0.40) | LMNANPSR1ACLYL3MBTL1TTR | |
| Hydrochloric Acid SCHEMBL9436666 | 0.77 | SLC9A1 (0.38) | — | |
| Hydrochloric Acid SCHEMBL9040257 | 0.74 | ACLY (0.34) | LMNANPSR1ACLYL3MBTL1RORC | |
| SCHEMBL6139690 | 0.70 | MAPT (0.53) | LMNAL3MBTL1TTRRORC | |
| SCHEMBL7948238 | 0.69 | LMNA (0.44) | LMNAACLYCA1CA2 | |
| SCHEMBL28790312 | 0.68 | CA12 (0.64) | CA12CA1CA2CA3CA4 | |
| SCHEMBL1495405 | 0.65 | KMT2A (0.62) | LMNAL3MBTL1 | |
| SCHEMBL28669838 | 0.65 | TSHR (0.57) | LMNAL3MBTL1TTR | |
| SCHEMBL9038640 | 0.65 | TTR (0.48) | LMNAACLYTTR | |
| SCHEMBL24572870 | 0.65 | MAPT (0.63) | LMNANPSR1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5373024-A | 3,5-Substituted benzoylguanidines, process for their preparation, their use as a medicament of diagnostic and medicament containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-12-13 | — | — | US | disclosed |