Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ACLY | P53396 | 9/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9436617 | 0.84 | LMNA (0.40) | LMNANPSR1L3MBTL1ACLYTTR | |
| Hydrochloric Acid SCHEMBL9436666 | 0.83 | SLC9A1 (0.38) | — | |
| Hydrochloric Acid SCHEMBL9040257 | 0.80 | ACLY (0.34) | LMNANPSR1L3MBTL1ACLYRORC | |
| SCHEMBL6139690 | 0.67 | MAPT (0.53) | LMNAL3MBTL1TTRRORCKMT2A | |
| SCHEMBL7948238 | 0.67 | LMNA (0.44) | LMNAACLY | |
| SCHEMBL7946304 | 0.66 | L3MBTL1 (0.40) | LMNANPSR1L3MBTL1ACLYPTGS2 | |
| SCHEMBL27824409 | 0.65 | KMO (0.48) | LMNARAB9AKMT2A | |
| SCHEMBL9436730 | 0.64 | PTGS2 (0.50) | ACLYPTGS2 | |
| SCHEMBL24572870 | 0.63 | MAPT (0.63) | LMNANPSR1KMT2A | |
| SCHEMBL9043010 | 0.63 | KDM4E (0.47) | LMNANPSR1ACLYTTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5373024-A | 3,5-Substituted benzoylguanidines, process for their preparation, their use as a medicament of diagnostic and medicament containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-12-13 | — | — | US | disclosed |