Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 9/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 4/20 | 0.34 |
| ▸ | MMP9 | P14780 | 3/20 | 0.34 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9437621 | 0.87 | HSD17B10 (0.39) | RENGAA | |
| SCHEMBL9437654 | 0.85 | KMT2A (0.41) | RENALDH1A1MEN1KMT2A | |
| SCHEMBL9437641 | 0.83 | AVPR1B (0.42) | RENALDH1A1MEN1KMT2A | |
| SCHEMBL9437653 | 0.79 | ALDH1A1 (0.39) | RENCA12CA2CA7CA9 | |
| SCHEMBL9437661 | 0.79 | ALDH1A1 (0.36) | RENCA12CA2CA7CA9 | |
| SCHEMBL9437659 | 0.79 | ALDH1A1 (0.34) | RENCA12CA2CA7CA9 | |
| SCHEMBL9437648 | 0.79 | MMP2 (0.36) | RENCA12CA2CA7CA9 | |
| SCHEMBL7339274 | 0.73 | TSHR (0.34) | RENCA12CA2CA7CA9 | |
| SCHEMBL7333230 | 0.72 | REN (0.49) | REN | |
| SCHEMBL7339453 | 0.70 | KMT2A (0.42) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332742-A | Ocular hypotensive | ABBOTT LABORATORIES (US) | 1994-07-26 | — | — | US | disclosed |