Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1B | P47901 | 3/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.40 |
| ▸ | REN | P00797 | 10/20 | 0.38 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9437621 | 0.96 | HSD17B10 (0.39) | AVPR1BCHRM1RENHSD17B10CTSB | |
| SCHEMBL9437654 | 0.85 | KMT2A (0.41) | RENMEN1ALDH1A1KMT2A | |
| SCHEMBL9437649 | 0.83 | REN (0.35) | RENMEN1ALDH1A1KMT2A | |
| SCHEMBL9437588 | 0.79 | CHRM1 (0.41) | AVPR1BCHRM1RENAPOBEC3AAPOBEC3G | |
| SCHEMBL9437628 | 0.79 | AVPR1B (0.40) | AVPR1BCHRM1RENAPOBEC3AAPOBEC3G | |
| SCHEMBL9437637 | 0.79 | ALDH1A1 (0.40) | AVPR1BCHRM1RENAPOBEC3AAPOBEC3G | |
| SCHEMBL9437651 | 0.79 | AVPR1B (0.40) | AVPR1BCHRM1RENAPOBEC3AAPOBEC3G | |
| SCHEMBL7332174 | 0.77 | MMP2 (0.51) | CHRM1MEN1ALDH1A1KMT2AHSD17B10 | |
| SCHEMBL7332179 | 0.77 | MMP2 (0.51) | CHRM1MEN1ALDH1A1KMT2AHSD17B10 | |
| SCHEMBL7338091 | 0.75 | ITGB3 (0.48) | AVPR1BCHRM1HSD17B10CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332742-A | Ocular hypotensive | ABBOTT LABORATORIES (US) | 1994-07-26 | — | — | US | disclosed |