Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 5/20 | 0.35 |
| ▸ | MMP9 | P14780 | 4/20 | 0.35 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | REN | P00797 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9437573 | 0.87 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL9437535 | 0.86 | REN (0.41) | ALDH1A1MEN1KMT2ASMN1; SMN2MMP2 | |
| SCHEMBL9437597 | 0.85 | MEN1 (0.49) | ALDH1A1MEN1KMT2ASMN1; SMN2REN | |
| SCHEMBL9437637 | 0.84 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2ALMNATP53 | |
| SCHEMBL9437659 | 0.82 | ALDH1A1 (0.34) | ALDH1A1MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL9437538 | 0.81 | ALDH1A1 (0.37) | ALDH1A1MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL9437661 | 0.80 | ALDH1A1 (0.36) | ALDH1A1MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL9437649 | 0.79 | REN (0.35) | ALDH1A1MEN1KMT2AMMP2MMP9 | |
| SCHEMBL9437648 | 0.78 | MMP2 (0.36) | ALDH1A1MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL7333230 | 0.72 | REN (0.49) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332742-A | Ocular hypotensive | ABBOTT LABORATORIES (US) | 1994-07-26 | — | — | US | disclosed |