Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9437794 | 0.86 | HTR1A (0.46) | HTR1AALDH1A1L3MBTL1PKMLMNA | |
| SCHEMBL9437929 | 0.85 | HTR1A (0.43) | HTR1AALDH1A1L3MBTL1PKMLMNA | |
| SCHEMBL9437814 | 0.81 | HTR1A (0.50) | HTR1AALDH1A1L3MBTL1PKMUSP2 | |
| SCHEMBL9437909 | 0.81 | HTR1A (0.46) | HTR1AALDH1A1L3MBTL1PKMLMNA | |
| SCHEMBL9437850 | 0.80 | SIGMAR1 (0.54) | HTR1AHTR2C | |
| SCHEMBL9437804 | 0.80 | L3MBTL1 (0.58) | HTR1AALDH1A1L3MBTL1PKMLMNA | |
| SCHEMBL9437932 | 0.78 | SIGMAR1 (0.49) | HTR1AHTR2C | |
| SCHEMBL9437888 | 0.75 | HTR1A (0.49) | HTR1AALDH1A1DRD2HTR2CHTR7 | |
| SCHEMBL9437973 | 0.74 | ALDH1A1 (0.40) | HTR1AALDH1A1L3MBTL1PKMLMNA | |
| SCHEMBL9437950 | 0.73 | HTR1A (0.45) | HTR1AALDH1A1DRD2HTR2CHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5296477-A | Antidepressants | ADIR ET COMPAGNIE (FR) | 1994-03-22 | — | — | US | disclosed |
| US-5196434-A | Antidepressants, anxiolytic agents | ADIR ET COMPAGNIE (FR) | 1993-03-23 | — | — | US | disclosed |