Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 10/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9437909 | 0.82 | HTR1A (0.46) | HTR1AALDH1A1L3MBTL1PKMHPGD | |
| SCHEMBL9437732 | 0.81 | HTR1A (0.46) | HTR1AALDH1A1L3MBTL1PKMUSP2 | |
| SCHEMBL9437912 | 0.79 | SIGMAR1 (0.56) | HTR1AACHE | |
| SCHEMBL9437804 | 0.77 | L3MBTL1 (0.58) | HTR1AALDH1A1L3MBTL1PKMTSHR | |
| SCHEMBL9437929 | 0.77 | HTR1A (0.43) | HTR1AALDH1A1L3MBTL1PKMHPGD | |
| SCHEMBL9437702 | 0.77 | SIGMAR1 (0.51) | HTR1AACHE | |
| SCHEMBL9437780 | 0.77 | SIGMAR1 (0.53) | HTR1AACHE | |
| SCHEMBL9437711 | 0.74 | SIGMAR1 (0.53) | HTR1AACHE | |
| SCHEMBL9437794 | 0.74 | HTR1A (0.46) | HTR1AALDH1A1L3MBTL1PKMUSP2 | |
| SCHEMBL9437869 | 0.74 | HTR1A (0.53) | HTR1AALDH1A1L3MBTL1PKMUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5296477-A | Antidepressants | ADIR ET COMPAGNIE (FR) | 1994-03-22 | — | — | US | disclosed |
| US-5268381-A | Antidepressant or anxiolytic compound | ADIR ET COMPAGNIE (FR) | 1993-12-07 | — | — | US | disclosed |