Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9437843 | 0.93 | ALDH1A1 (0.44) | TPSAB1CA12CA2CA9ALDH1A1 | |
| SCHEMBL9437777 | 0.83 | ALDH1A1 (0.42) | CA12CA2CA9ALDH1A1MEN1 | |
| SCHEMBL9437790 | 0.83 | TSHR (0.41) | CA12CA2CA9ALDH1A1MEN1 | |
| SCHEMBL9437864 | 0.79 | HTR1A (0.43) | TPSAB1CA12CA2CA9ALDH1A1 | |
| SCHEMBL9437775 | 0.78 | SIGMAR1 (0.36) | — | |
| SCHEMBL8100564 | 0.74 | SIGMAR1 (0.49) | — | |
| SCHEMBL8869700 | 0.74 | SIGMAR1 (0.49) | — | |
| SCHEMBL9437754 | 0.74 | MAPT (0.48) | TPSAB1CA12CA2CA9ALDH1A1 | |
| SCHEMBL9437738 | 0.74 | SIGMAR1 (0.52) | — | |
| SCHEMBL9437753 | 0.72 | SIGMAR1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5296477-A | Antidepressants | ADIR ET COMPAGNIE (FR) | 1994-03-22 | — | — | US | disclosed |