Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 3/20 | 0.41 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | NMT1 | P30419 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9437806 | 0.87 | TSHR (0.45) | HTR1APOLBHTR2CPKMCA12 | |
| SCHEMBL9437824 | 0.87 | TSHR (0.43) | HTR1APOLBHTR2CPKMCA12 | |
| SCHEMBL9437844 | 0.84 | MAPK1 (0.44) | HTR1APOLBHTR2CPKMALDH1A1 | |
| SCHEMBL9437743 | 0.84 | TSHR (0.43) | HTR1APOLBHTR2CPKMCA12 | |
| SCHEMBL9437746 | 0.83 | TSHR (0.46) | HTR1APOLBHTR2CPKMCA12 | |
| SCHEMBL9437756 | 0.79 | TPSAB1 (0.43) | HTR1APOLBTPSAB1PKMCA12 | |
| SCHEMBL9437726 | 0.79 | HTR1A (0.51) | HTR1AHTR2CNMT1GABRA1GABRA5 | |
| SCHEMBL9437796 | 0.75 | HTR1A (0.54) | HTR1AHTR2CGABRA1GABRA5HTR1D | |
| SCHEMBL9437818 | 0.75 | HTR1A (0.49) | HTR1AHTR2CNMT1GABRA1GABRA5 | |
| SCHEMBL9437754 | 0.74 | MAPT (0.48) | TPSAB1CA12CA2CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5296477-A | Antidepressants | ADIR ET COMPAGNIE (FR) | 1994-03-22 | — | — | US | claimed |
| US-5296477-A | Antidepressants | ADIR ET COMPAGNIE (FR) | 1994-03-22 | — | — | US | disclosed |
| US-5268381-A | Antidepressant or anxiolytic compound | ADIR ET COMPAGNIE (FR) | 1993-12-07 | — | — | US | disclosed |