Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 3/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9437746 | 0.95 | TSHR (0.46) | MAPK1HSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL9437743 | 0.94 | TSHR (0.43) | MAPK1HSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL9437824 | 0.91 | TSHR (0.43) | MAPK1HSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL9437806 | 0.91 | TSHR (0.45) | MAPK1HSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL9437864 | 0.84 | HTR1A (0.43) | ALDH1A1MEN1KMT2APOLBHTR1A | |
| SCHEMBL9593875 | 0.84 | HTR1A (0.50) | HSD17B10TSHRHTR1AHTR2CGABRA1 | |
| SCHEMBL9437820 | 0.80 | PKM (0.54) | MEN1KMT2APOLBPKM | |
| SCHEMBL9437777 | 0.79 | ALDH1A1 (0.42) | MAPK1HSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL9437846 | 0.79 | HTR1A (0.46) | HSD17B10TSHRHTR1AHTR2CGABRA1 | |
| SCHEMBL9437916 | 0.76 | HTR1A (0.46) | HSD17B10TSHRHTR1AHTR2CGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5296477-A | Antidepressants | ADIR ET COMPAGNIE (FR) | 1994-03-22 | — | — | US | disclosed |
| US-5268381-A | Antidepressant or anxiolytic compound | ADIR ET COMPAGNIE (FR) | 1993-12-07 | — | — | US | disclosed |
| US-5196434-A | Antidepressants, anxiolytic agents | ADIR ET COMPAGNIE (FR) | 1993-03-23 | — | — | US | disclosed |