Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | THRB | P10828 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MMP12 | P39900 | 1/20 | 0.45 |
| ▸ | PRNP | P04156 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | DRD4 | P21917 | 2/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9437774 | 0.95 | PKM (0.52) | PKMRAB9ATHRBLMNAKMT2A | |
| SCHEMBL9437717 | 0.94 | PKM (0.51) | PKMRAB9ATHRBLMNAKMT2A | |
| SCHEMBL9437844 | 0.80 | MAPK1 (0.44) | PKMKMT2AMEN1POLB | |
| SCHEMBL9437740 | 0.79 | PARP1 (0.60) | PARP1MMP12PRNPDRD2DRD4 | |
| SCHEMBL9437746 | 0.75 | TSHR (0.46) | PKMKMT2AMEN1POLB | |
| SCHEMBL4271023 | 0.74 | MMP12 (0.70) | PKMRAB9ATHRBLMNAKMT2A | |
| SCHEMBL9437743 | 0.74 | TSHR (0.43) | PKMKMT2AMEN1POLB | |
| SCHEMBL9437878 | 0.74 | PARP1 (0.51) | PARP1DRD2DRD4DRD3 | |
| SCHEMBL12691657 | 0.73 | ALDH1A1 (0.63) | KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9437826 | 0.73 | PARP1 (0.49) | PARP1DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5296477-A | Antidepressants | ADIR ET COMPAGNIE (FR) | 1994-03-22 | — | — | US | disclosed |
| US-5268381-A | Antidepressant or anxiolytic compound | ADIR ET COMPAGNIE (FR) | 1993-12-07 | — | — | US | disclosed |