Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9437718 | 0.90 | ALDH1A1 (0.50) | HTR1AALDH1A1PKML3MBTL1SLC6A2 | |
| Hydrochloric Acid SCHEMBL10981754 | 0.88 | ALDH1A1 (0.49) | HTR1AALDH1A1PKML3MBTL1SLC6A2 | |
| SCHEMBL8109737 | 0.86 | HTR1A (0.53) | HTR1AALDH1A1PKML3MBTL1SLC6A2 | |
| SCHEMBL10393719 | 0.84 | HTR1A (0.51) | HTR1AALDH1A1PKML3MBTL1SLC6A2 | |
| SCHEMBL9464160 | 0.84 | KDM4E (0.51) | HTR1AALDH1A1PKML3MBTL1SLC6A2 | |
| SCHEMBL13156347 | 0.83 | PKM (0.49) | HTR1AALDH1A1PKML3MBTL1SLC6A2 | |
| SCHEMBL9463980 | 0.82 | HTR1A (0.49) | HTR1AALDH1A1PKML3MBTL1SLC6A2 | |
| SCHEMBL5658301 | 0.81 | PKM (0.50) | HTR1AALDH1A1PKML3MBTL1SLC6A2 | |
| SCHEMBL8109023 | 0.81 | ALDH1A1 (0.50) | HTR1AALDH1A1PKML3MBTL1SLC6A2 | |
| SCHEMBL9464205 | 0.80 | HTR1A (0.61) | HTR1APKMSLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5296477-A | Antidepressants | ADIR ET COMPAGNIE (FR) | 1994-03-22 | — | — | US | disclosed |
| US-5268381-A | Antidepressant or anxiolytic compound | ADIR ET COMPAGNIE (FR) | 1993-12-07 | — | — | US | disclosed |
| US-5196434-A | Antidepressants, anxiolytic agents | ADIR ET COMPAGNIE (FR) | 1993-03-23 | — | — | US | disclosed |
| EP-0478446-A1 | Heterocyclic alkylamines, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1992-04-01 | — | — | EP | disclosed |