SCHEMBL9439352

SCHEMBL9439352

C=CC[C@@]1(O)[C@](O)(CC=C)[C@@](O)(Cc2ccccc2)[C@@H](O)[C@@H](O)[C@]1(O)Cc1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.34
BCHE P06276 1/20 0.33
LMNA P02545 2/20 0.33
HTT P42858 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
MAOA P21397 4/20 0.32
MAOB P27338 4/20 0.32
GAA P10253 1/20 0.32
MAPT P10636 1/20 0.32
MMP9 P14780 1/20 0.31
KDM1A O60341 2/20 0.31
OPRL1 P41146 2/20 0.30
HSD11B1 P28845 1/20 0.30
OPRM1 P35372 1/20 0.30
OPRD1 P41143 1/20 0.30
OPRK1 P41145 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9439494 1.00 ALDH1A1 (0.34) ALDH1A1BCHELMNAHTTNPSR1
SCHEMBL10375420 0.85 ALDH1A1 (0.30) ALDH1A1
SCHEMBL9053809 0.81 ALDH1A1 (0.40) ALDH1A1LMNAMAOAMAOBKDM1A
SCHEMBL10604754 0.74 MMP9 (0.33) MMP9
SCHEMBL9439807 0.72 LTA4H (0.40) ALDH1A1L3MBTL1TSHR
SCHEMBL6922576 0.71 MAOA (0.38) ALDH1A1LMNAMAOAMAOBKDM1A
SCHEMBL9767801 0.71 MAOA (0.38) ALDH1A1LMNAMAOAMAOBKDM1A
SCHEMBL9767803 0.71 MAOA (0.38) ALDH1A1LMNAMAOAMAOBKDM1A
SCHEMBL9439398 0.69 MEN1 (0.39) ALDH1A1LMNAHTTNPSR1L3MBTL1
SCHEMBL7437205 0.69 LMNA (0.40) ALDH1A1LMNAHTTNPSR1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5292913-A Labeling with deuterium or tritium MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1994-03-08 US disclosed
EP-0262227-B1 PROCESS FOR THE PREPARATION OF MYOINOSITOL DERIVATIVES MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-01-20 EP disclosed
US-4952717-A Myoinositol derivatives and preparation process thereof MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1990-08-28 US disclosed
EP-0262227-A1 Process for the preparation of myoinositol derivatives MITSUI TOATSU CHEMICALS, Inc. (JP) 1988-04-06 EP disclosed