Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SCN4A | P35499 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5857537 | 0.79 | LMNA (0.33) | LMNATSHRMAPK1SCN4ASCN5A | |
| SCHEMBL8611475 | 0.74 | KIF11 (0.33) | LMNATSHRMAPK1SCN4ASCN5A | |
| SCHEMBL7031865 | 0.73 | KMT2A (0.35) | LMNATSHRMAPK1SCN4ASCN5A | |
| SCHEMBL10586576 | 0.72 | KDM4E (0.34) | KIF11 | |
| SCHEMBL29701281 | 0.72 | KDM4E (0.34) | KIF11 | |
| SCHEMBL21461362 | 0.71 | — | — | |
| SCHEMBL461337 | 0.70 | THRB (0.40) | KIF11 | |
| SCHEMBL8491987 | 0.69 | TDP1 (0.35) | MAPK1KMT2AMAPTKIF11 | |
| SCHEMBL9899733 | 0.69 | THRB (0.35) | MAPK1KMT2AMAPTKIF11 | |
| SCHEMBL9848988 | 0.69 | CES2 (0.33) | LMNATSHRMAPK1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5294375-A | Thermochromic materials | POLAROID CORPORATION (US) | 1994-03-15 | — | — | US | disclosed |