Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.33 |
| ▸ | CES1 | P23141 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7064342 | 0.76 | KDM4E (0.36) | KDM4EPKMUSP2MEN1OPRK1 | |
| SCHEMBL29042467 | 0.72 | KDM4E (0.33) | KDM4EPKMMEN1OPRK1KMT2A | |
| SCHEMBL2161308 | 0.72 | KDM4E (0.35) | KDM4EPKM | |
| SCHEMBL11456794 | 0.70 | BID (0.43) | KDM4EMAPT | |
| SCHEMBL9518749 | 0.70 | KIF11 (0.35) | KIF11LMNA | |
| SCHEMBL21385037 | 0.69 | KDM4E (0.31) | KDM4EPKMOPRK1 | |
| SCHEMBL5857537 | 0.69 | LMNA (0.33) | KDM4EPKMKIF11LMNAKMT2A | |
| SCHEMBL9440141 | 0.69 | LMNA (0.34) | KIF11LMNAMAPTKMT2ATSHR | |
| SCHEMBL28431200 | 0.69 | KIF11 (0.37) | KDM4EPKMKIF11CYP3A4MEN1 | |
| SCHEMBL8611475 | 0.68 | KIF11 (0.33) | KDM4EKIF11LMNAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0407032-A2 | Aromatic and heteroaromatic amines for treating depressions, cerebral insufficiency disorders or dementia | JOHN WYETH & BROTHER LIMITED (GB) | 1991-01-09 | — | — | EP | disclosed |
| EP-0346841-A2 | 1-Aryl-naphthoic acid amide and microbicides containing these | CIBA-GEIGY AG (CH) | 1989-12-20 | — | — | EP | disclosed |