SCHEMBL9440516

SCHEMBL9440516

COc1cc(C=C(CCCC[SiH](O[Si](C)(C)C)O[Si](C)(C)C)C(=O)O)cc(OC)c1OC

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
HTR1A P08908 2/20 0.39
ALDH1A1 P00352 2/20 0.39
KDM4E B2RXH2 1/20 0.39
HPGD P15428 1/20 0.39
HTR2C P28335 1/20 0.39
HSD17B10 Q99714 1/20 0.39
GAA P10253 2/20 0.36
HTT P42858 1/20 0.36
MAPK1 P28482 2/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
PSMB11 A5LHX3 1/20 0.34
PSMA7 O14818 1/20 0.34
PSMB1 P20618 1/20 0.34
PSMA1 P25786 1/20 0.34
PSMA2 P25787 1/20 0.34
PSMA3 P25788 1/20 0.34
PSMA4 P25789 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9440566 0.83 POLB (0.40) POLBMEN1KMT2AHTR1AALDH1A1
SCHEMBL9119119 0.81 POLB (0.41) POLBMEN1KMT2AHTR1AALDH1A1
SCHEMBL10610363 0.79 HTR1A (0.52) POLBMEN1KMT2AHTR1AALDH1A1
SCHEMBL10606243 0.79 HTR1A (0.52) POLBMEN1KMT2AHTR1AALDH1A1
SCHEMBL28310756 0.79 ALOX5 (0.51) POLBMEN1KMT2AHTR1AALDH1A1
SCHEMBL9119704 0.79 MEN1 (0.39) POLBMEN1KMT2AHTR1AALDH1A1
SCHEMBL9440575 0.77 POLB (0.38) POLBMEN1KMT2AHTR1AALDH1A1
SCHEMBL28310745 0.76 HTR1A (0.50) POLBMEN1KMT2AHTR1AALDH1A1
SCHEMBL645502 0.76 MEN1 (0.38) POLBMEN1KMT2AHTR1AALDH1A1
SCHEMBL9440505 0.75 ABCB1 (0.57) ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5315022-A Sunscreen SHISEIDO COMPANY LTD. (JP) 1994-05-24 US disclosed