Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX12 | P18054 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.36 |
| ▸ | FABP3 | P05413 | 2/20 | 0.35 |
| ▸ | FABP4 | P15090 | 2/20 | 0.35 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.34 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 2/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12248238 | 0.81 | ALOX12 (0.41) | ALOX12HIF1AALDH1A1GAAHTT | |
| SCHEMBL23901712 | 0.78 | ALDH1A1 (0.38) | ALOX12HIF1AALDH1A1GAAHTT | |
| SCHEMBL29630154 | 0.72 | LMNA (0.46) | ALOX12HIF1AALDH1A1GAAHTT | |
| SCHEMBL778017 | 0.72 | LMNA (0.46) | ALOX12HIF1AALDH1A1GAAHTT | |
| SCHEMBL7063441 | 0.72 | ALOX12 (0.34) | ALOX12HIF1AALDH1A1GAAHTT | |
| SCHEMBL7064997 | 0.71 | LMNA (0.35) | ALOX12HIF1AALDH1A1GAAHTT | |
| SCHEMBL23901710 | 0.71 | ALDH1A1 (0.33) | ALOX12HIF1AALDH1A1GAAHTT | |
| SCHEMBL598620 | 0.69 | LMNA (0.60) | ALOX12HIF1AALDH1A1GAAHTT | |
| SCHEMBL30632575 | 0.69 | LMNA (0.60) | ALOX12HIF1AALDH1A1GAAHTT | |
| SCHEMBL9909702 | 0.68 | CRHR1 (0.42) | ALOX12HIF1AALDH1A1GAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5354484-A | Improved high temperature stability | THE LUBRIZOL CORPORATION (US) | 1994-10-11 | — | — | US | disclosed |